
In addition to the special efficacy in treating bruises and injuries, Panax notoginseng also has the function of nourishing and strengthening the body. Modern pharmacological studies have shown that Panax notoginseng has obvious preventive and therapeutic effects on hyperlipidemia, hyperviscosemia, hypertension, arrhythmia, etc. The main effective component of the above-ground part of Panax notoginseng, the total saponins of Panax notoginseng leaves, have pharmacological effects such as sedation, analgesia, and lipid-lowering.
Effects on the central nervous system: The dosage of 100-200mg/kg of Panax notoginseng leaf glycosides can significantly reduce the spontaneous activities of mice, enhance the sedative and hypnotic effects of thiopental sodium, pentobarbital sodium, etc., and can antagonize the excitatory effect caused by the central stimulant caffeine, indicating that this product has a significant inhibitory effect on the central nervous system. The saponins of Panax notoginseng leaves can improve the blood supply to the brain, nourish and regulate the nerves, restore the coordination of various regulatory functions of the nervous system, and thus restore physiological sleep to treat neurasthenia. It can also enhance the inhibitory effect of the cerebral cortex, reduce the excitability of the subcortex, and play a role in resisting anxiety, which can be used to treat generalized anxiety disorder.
The saponins of Panax notoginseng leaves can significantly shorten the time to fall asleep, prolong the sleep time, reduce the number of awakenings, and improve headaches, dizziness, palpitations, and fatigue. The total effective rate in treating neurasthenia is significantly higher than that of the gastrodin control group.
The saponins of Panax notoginseng leaves can significantly reduce the contents of serum total cholesterol (TC) and serum triglyceride (TG) in two hyperlipidemia model animals, rats and quails. This effect is related to the ginsenoside二醇 type saponin components contained in it. It has been reported that TC is reduced by an average of 22.4%, TG is reduced by an average of 37.7%, and high-density lipoprotein increases by an average of 18.8%. Using the self-control method, patients diagnosed with hyperlipidemia take 100mg of Panax notoginseng leaf glycosides three times a day, with a course of treatment of 60 days, and the total effective rate is 81.6%.